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专利名称：Sefuarosuhorinjudotaioyobigaijudotaioganju…

发明人：MUTOSHIGEAKI,NIIMURAKOICHI,ANDO

TAKAO,FUJIIMASAHIKO,FUJII

TAKAMI,SUGANOAKIHIKO,FURUSHO

TAKAO,YOSHIKUMICHIKAO

申请号：JP23455282

申请日：19821229

公开号：JPH0235759B2

公开日：19900813

专利内容由知识产权出版社提供

摘要：NEWMATERIAL:ThecompoundofformulaI[R1isH,OH,-CONH2,loweralkyl

orgroupofformulaII(mis0or1);nis0-2;includingitssaltandester);lis0-2;XisCorN].

EXAMPLE:N-(4-Carbomethoxymethylphenyl)-7-(adamantan-1-acetamido

):ostthe

antibacterialactivitybythechemicalmodification,however,theactivityisrecoveredwhen

S:Theobjectivecompoundispreparedbyreacting

the7-(adamantan-1-acetamido)cephalosporanicacid(oritsreactivederivative)of

formulaIVwiththecompoundofformulaV(oritssalt)(e.g.4-aminophenylaceticacid)

usuallyinasolventsuchasacetone,preferablyat-30-+0.5-48hr.

申请人：KUREHACHEMICALINDCOLTD

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